Last five starts against the White Sox, "Catfish" Guthrie has allowed two earned runs in 35 and 2/3rd's innings.
When the Sox scored their only run in the 5th inning it snapped a 21 inning shutout streak he had going against them. Bet your bottom dollar the Royals are going to try to pitch this guys against the Sox in every series much like Verlander does with the Tigers.
In 14 of the last 21 meetings between the two teams the Sox have scored three runs or less. They are 3-11 in those games.
Oh by the way, it's "Cy" Chen, "The Great" Mendoza and "Catfish" Guthrie.